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Engtm1Mle
Targeted Allele Detail
Nomenclature
Symbol: Engtm1Mle
Name: endoglin; targeted mutation 1, Michelle Letarte
MGI ID: MGI:2177824
Synonyms: End -, Eng-
Gene: Eng  Location: Chr2:32646595-32682658 bp, + strand  Genetic Position: Chr2, 22.09 cM
Arrest in development in Engtm1Mle/Engtm1Mle embryos

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58502
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 31 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eng Mutation:  14 strains or lines available
References
Original:  J:58502 Bourdeau A, et al., A murine model of hereditary hemorrhagic telangiectasia [see comments]. J Clin Invest. 1999 Nov;104(10):1343-51
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory