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Engtm1Dyl
Targeted Allele Detail
Nomenclature
Symbol: Engtm1Dyl
Name: endoglin; targeted mutation 1, Dean Y Li
MGI ID: MGI:2177823
Synonyms: Eng-
Gene: Eng  Location: Chr2:32646595-32682669 bp, + strand  Genetic Position: Chr2, 22.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:55403
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced the first two exons of the gene. (J:55403)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eng Mutation:  34 strains or lines available
References
Original:  J:55403 Li DY, et al., Defective angiogenesis in mice lacking endoglin. Science. 1999 May 28;284(5419):1534-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/06/2018
MGI 6.11
The Jackson Laboratory