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Lmo2tm1Thr
Targeted Allele Detail
Summary
Symbol: Lmo2tm1Thr
Name: LIM domain only 2; targeted mutation 1, Terence H Rabbitts
MGI ID: MGI:2177821
Synonyms: rbtn2 -
Gene: Lmo2  Location: Chr2:103788340-103812223 bp, + strand  Genetic Position: Chr2, 54.46 cM
Alliance: Lmo2tm1Thr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:19175
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin selection cassette was inserted into exon 2. Northern blot analysis on embryonic RNA derived from homozygous mice confirmed that no transcript was produced from this allele. (J:19175)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo2 Mutation:  31 strains or lines available
References
Original:  J:19175 Warren AJ, et al., The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development. Cell. 1994 Jul 15;78(1):45-57
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory