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Bsgtm1Tmu
Targeted Allele Detail
Nomenclature
Symbol: Bsgtm1Tmu
Name: basigin; targeted mutation 1, Takashi Muramatsu
MGI ID: MGI:2177802
Synonyms: Bsg-
Gene: Bsg  Location: Chr10:79704491-79711969 bp, + strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46376
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced 200 bp of the first exon, containing sequences encoding the signal peptide. Northern blot analysis on RNA derived from testis and cerebrum of homozygous mice confirmed that no detectable transcript was produced from this allele. Western blot analysis on extracts detived form testis and uterus of homozygous mice confirmed that no detectable protein is expressed from this allele. (J:46376)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bsg Mutation:  6 strains or lines available
References
Original:  J:46376 Igakura T, et al., A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis. Dev Biol. 1998 Feb 15;194(2):152-65
All:  18 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory