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Gabrg2tm1Lusc
Targeted Allele Detail
Summary
Symbol: Gabrg2tm1Lusc
Name: gamma-aminobutyric acid type A receptor, subunit gamma 2; targeted mutation 1, Bernhard Luscher
MGI ID: MGI:2177608
Synonyms: gamma2-, gamma20
Gene: Gabrg2  Location: Chr11:41801030-41891684 bp, - strand  Genetic Position: Chr11, 24.8 cM
Alliance: Gabrg2tm1Lusc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:28662
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin selection cassette replaced a genomic fragment containing exon 8. (J:28662)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gabrg2 Mutation:  41 strains or lines available
References
Original:  J:28662 Gunther U, et al., Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7749-53
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory