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Erbb2tm2.1Cbm
Targeted Allele Detail
Nomenclature
Symbol: Erbb2tm2.1Cbm
Name: erb-b2 receptor tyrosine kinase 2; targeted mutation 2.1, Carmen Birchmeier
MGI ID: MGI:2177256
Synonyms: Erbb2delta
Gene: Erbb2  Location: Chr11:98412470-98437716 bp, + strand  Genetic Position: Chr11, 61.75 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75421
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is a derivative of Erbb2tm2Cbr in which the loxP flanked sequences were deleted in vivo by crossing mice carrying this allele to mice carrying the TgN(CMV-Cre)1Cgn transgene. (J:75421)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Erbb2 Mutation:  21 strains or lines available
References
Original:  J:75421 Garratt AN, et al., A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool. J Cell Biol. 2000 Mar 6;148(5):1035-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory