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Tg(Ckmm-cre)1Lrsn
Transgene Detail
Summary
Symbol: Tg(Ckmm-cre)1Lrsn
Name: transgene insertion 1, Nils-Goran Larsson
MGI ID: MGI:2177173
Synonyms: Ckm-cre, Ckmm-cre, MCK-cre
Transgene: Tg(Ckmm-cre)1Lrsn  Location: unknown  Genetic Position: Chr10, Syntenic
Alliance: Tg(Ckmm-cre)1Lrsn page
Heart histology of Tfamtm1Lrsn/Tfamtm1Lrsn Tg(Ckmm-cre)1Lrsn/0 mice

Show the 1 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Ckmm-cre)1Lrsn expression driven by 1 gene
 
Mutation detailsA 6.5 kb genomic DNA fragment of the Ckmm gene containing the promoter and enhancer 1, untranslated exon 1, 3kb of intron 1 including the enhancer 2 region, and the first 16 bp of exon 2 drives expression of cre. Cre is active in heart and skeletal muscle starting approximately at embryonic day 13. (J:51964)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ckm (species not specified)
Summary of all recombinase alleles driven by Ckm.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:51964 Wang J, et al., Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat Genet. 1999 Jan;21(1):133-7
All:  32 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory