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Admtm1Unc
Targeted Allele Detail
Nomenclature
Symbol: Admtm1Unc
Name: adrenomedullin; targeted mutation 1, University of North Carolina
MGI ID: MGI:2176598
Synonyms: AM-
Gene: Adm  Location: Chr7:110627669-110629819 bp, + strand  Genetic Position: Chr7, 57.7 cM
Massive generalized edema of Admtm1Unc/Admtm1Unc embryos

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67044
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adm Mutation:  1 strain or line available
References
Original:  J:67044 Caron KM, et al., Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):615-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory