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Runx2tm1Mjo
Targeted Allele Detail
Nomenclature
Symbol: Runx2tm1Mjo
Name: runt related transcription factor 2; targeted mutation 1, Michael J Owen
MGI ID: MGI:2176465
Synonyms: Cbfa1-, Runx2-, Runx2LacZ
Gene: Runx2  Location: Chr17:44495987-44814797 bp, - strand  Genetic Position: Chr17, 21.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40784
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 210 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx2 Mutation:  2 strains or lines available
Notes
ES cell line = GK129 and R1.3

References
Original:  J:40784 Otto F, et al., Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development [see comments]. Cell. 1997 May 30;89(5):765-71
All:  43 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory