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Il4tm1Kopf
Targeted Allele Detail
Nomenclature
Symbol: Il4tm1Kopf
Name: interleukin 4; targeted mutation 1, Manfred Kopf
MGI ID: MGI:2176268
Synonyms: IL-4-, IL-4null
Gene: Il4  Location: Chr11:53602982-53618669 bp, - strand  Genetic Position: Chr11, 31.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:14593
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette was inserted into the third exon of the gene. (J:14593)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:  17 strains or lines available
References
Original:  J:14593 Kopf M, et al., Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature. 1993 Mar 18;362(6417):245-8
All:  56 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory