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Tg(CMV-cre)1Cgn
Transgene Detail
Nomenclature
Symbol: Tg(CMV-cre)1Cgn
Name: transgene insertion 1, University of Cologne
MGI ID: MGI:2176180
Synonyms: CMV-Cre, CMV:Cre, Cre deleter, DCre, deleter, TgN(CMV-Cre)#Cgn, ubi-cre
Transgene: Tg(CMV-cre)1Cgn  Location: unknown  Genetic Position: ChrX, Syntenic
Transgene
origin
Strain of Origin:  BALB/cJ
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThis transgene expresses Cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most cells and tissues. (J:75204)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CMV     Summary of all recombinase alleles driven by CMV.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Notes
Homozygous transgenic mice are viable and fertile. The transgene appears to be X-linked since transgene transmission through males is restricted to female offspring.

In transgenic mice, in conjunction with a transgene carrying a loxP-flanked gene, deletion of the loxP-flanked gene occurs in all tissues including germ cells.

References
Original:  J:75204 Schwenk F, et al., A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 1995 Dec 25;23(24):5080-1
All:  755 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory