About   Help   FAQ
Meox2tm1(cre)Sor
Targeted Allele Detail
Nomenclature
Symbol: Meox2tm1(cre)Sor
Name: mesenchyme homeobox 2; targeted mutation 1, Philippe Soriano
MGI ID: MGI:2176174
Synonyms: Meox2Cre, Meox2-Cre, Meox2CreSor, MORE, More-cre, Mox2Cre, Mox2Cre, Mox2 Cre, Mox2-Cre, MoxCre
Gene: Meox2  Location: Chr12:37108546-37179528 bp, + strand  Genetic Position: Chr12, 16.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60933
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsAn nls-cre gene was inserted at the initiator ATG of the gene, followed by a neomycin selection cassette. The endogenous regulatory sequences drive expression by E5 in the epiblast and by E7 expression is detectable in all primitive ectoderm but not endoderm or trophectoderm. (J:60933, J:105278, J:132360)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Meox2     Summary of all recombinase alleles driven by Meox2. Comparative matrix view of recombinase activities
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 23 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Meox2 Mutation:  5 strains or lines available
References
Original:  J:60933 Tallquist MD, et al., Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis. 2000 Feb;26(2):113-5
All:  257 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory