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Shc1tm1Pgp
Targeted Allele Detail
Nomenclature
Symbol: Shc1tm1Pgp
Name: src homology 2 domain-containing transforming protein C1; targeted mutation 1, Pier G Pelicci
MGI ID: MGI:2159438
Synonyms: p66shc, p66shc-, p66Shc-
Gene: Shc1  Location: Chr3:89418551-89430029 bp, + strand  Genetic Position: Chr3, 39.11 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58535
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation detailsThis allele is a targeted mutation of the exon that encodes the CH2 region. Further details are referenced as "in preparation". (J:58535)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shc1 Mutation:  58 strains or lines available
References
Original:  J:58535 Migliaccio E, et al., The p66shc adaptor protein controls oxidative stress response and life span in mammals [see comments]. Nature. 1999 Nov 18;402(6759):309-13
All:  48 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory