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Drd1tm1Stl
Targeted Allele Detail
Nomenclature
Symbol: Drd1tm1Stl
Name: dopamine receptor D1; targeted mutation 1, Susumu Tonegawa
MGI ID: MGI:2159306
Synonyms: D1-, D1R-
Gene: Drd1  Location: Chr13:54051183-54055658 bp, - strand  Genetic Position: Chr13, 28.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:21603
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A PGK-neomycin based targeting vector replaced the 95% of the coding region. (J:21603)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Drd1 Mutation:  50 strains or lines available
References
Original:  J:21603 Xu M, et al., Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell. 1994 Nov 18;79(4):729-42
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory