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Mas1tm1Bdr
Targeted Allele Detail
Nomenclature
Symbol: Mas1tm1Bdr
Name: MAS1 oncogene; targeted mutation 1, Michael Bader
MGI ID: MGI:2158808
Synonyms: Mas -
Gene: Mas1  Location: Chr17:12841079-12868143 bp, - strand  Genetic Position: Chr17, 8.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:47445
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced sequences encoding the amino-terminal 253 amino acids of the protein. RNAse protection assays on RNA derived from brain and testis of homozygous mice confirmed that no transcript containing coding sequences is produced from this allele. (J:47445)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 57 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mas1 Mutation:  11 strains or lines available
References
Original:  J:47445 Walther T, et al., Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene. J Biol Chem. 1998 May 8;273(19):11867-73
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory