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Npy1rtm1Tped
Targeted Allele Detail
Nomenclature
Symbol: Npy1rtm1Tped
Name: neuropeptide Y receptor Y1; targeted mutation 1, Thierry Pedrazzini
MGI ID: MGI:2158699
Synonyms: NPY-, Npyr1-, Y1-
Gene: Npy1r  Location: Chr8:66697192-66706792 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:47972
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaces most of the second exon encoding the fifth transmembrane domain and a part of the interrupting intron. (J:47972)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:  12 strains or lines available
References
Original:  J:47972 Pedrazzini T, et al., Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor [see comments]. Nat Med. 1998 Jun;4(6):722-6
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory