About   Help   FAQ
Men1tm1Ctre
Targeted Allele Detail
Nomenclature
Symbol: Men1tm1Ctre
Name: multiple endocrine neoplasia 1; targeted mutation 1, Judy S Crabtree
MGI ID: MGI:2158697
Synonyms: Men1l, Men1loxP, Men1TSM
Gene: Men1  Location: Chr19:6334979-6340891 bp, + strand  Genetic Position: Chr19, 4.45 cM, cytoband A
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67128
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP-flanked neomycin selection cassette was inserted into intron 2 and a third loxP site was inserted into intron 8. (J:67128)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Men1 Mutation:  17 strains or lines available
References
Original:  J:67128 Crabtree JS, et al., A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1118-23
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory