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Bcl6tm2Rdf
Targeted Allele Detail
Nomenclature
Symbol: Bcl6tm2Rdf
Name: B cell leukemia/lymphoma 6; targeted mutation 2, Riccardo Dalla-Favera
MGI ID: MGI:2158438
Synonyms: BCL-6-
Gene: Bcl6  Location: Chr16:23965052-23988852 bp, - strand  Genetic Position: Chr16, 15.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40769
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic fragment containing exons 4 through part of exon 10 was replaced with a neomycin selection cassette. Nearly all of the coding sequences were deleted in this allele. (J:40769)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl6 Mutation:  22 strains or lines available
References
Original:  J:40769 Ye BH, et al., The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet. 1997 Jun;16(2):161-70
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory