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Coq7tm1Tsh
Targeted Allele Detail
Nomenclature
Symbol: Coq7tm1Tsh
Name: demethyl-Q 7; targeted mutation 1, Takuji Shirsawa
MGI ID: MGI:2158322
Synonyms: coq7-
Gene: Coq7  Location: Chr7:118509659-118533356 bp, - strand  Genetic Position: Chr7, 63.44 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73111
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exon 2. Western blot analysis did not detect immunoreactivity in homozygous mutant E9.5 embryo extracts. (J:73111)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Coq7 Mutation:  12 strains or lines available
References
Original:  J:73111 Nakai D, et al., Mouse Homologue of coq7/clk-1, Longevity Gene in Caenorhabditis elegans, Is Essential for Coenzyme Q Synthesis, Maintenance of Mitochondrial Integrity, and Neurogenesis. Biochem Biophys Res Commun. 2001 Nov 30;289(2):463-71
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory