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VisplNZB/BlNJ
QTL Variant Detail
Summary
QTL variant: VisplNZB/BlNJ
Name: visual placing; NZB/BlNJ
MGI ID: MGI:2157989
QTL: Vispl  Location: Chr11:118022590-118022724 bp  Genetic Position: Chr11, cM position of peak correlated region/allele: 82.96 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  NZB/BlNJ
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers later appearance of visual placing behavior compared to C57BL/6By. (J:53794)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:53794

Nineteen measures of sensorial, motor and body weight were subject to analysis in 389 female and male mice derived from reciprocal F1 and F2 mating of strains C57BL6/By and NZB/BlNJ . These traits were mapped via QTL analysis. In total 36 traits were mapped to chromosomes of which a number reached a threshold LOD score of 3.13 and were thus concidered significant. One such QTL, visual placing (vispl) mapped with mouse Chromosome 11 marker D11Mit48 with a LOD score of 4.05. NZB/BlNJ-derived alleles confer later appearance of visual placing behavior compared to C57BL/6By. This was measured the day after eyelid opening by suspending pups by the tail and lowering them towards a pencil without the vibrissae touching it. The pup was observed whether or notit extended the paw to grasp the pencil.

References
Original:  J:53794 Le Roy I, et al., Preweanling sensorial and motor development in laboratory mice: quantitative trait loci mapping. Dev Psychobiol. 1999 Mar;34(2):139-58
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory