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Apobec1tm1Rub
Targeted Allele Detail
Nomenclature
Symbol: Apobec1tm1Rub
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1; targeted mutation 1, Edward M Rubin
MGI ID: MGI:2157378
Synonyms: Apobec-, apobec-1delta6
Gene: Apobec1  Location: Chr6:122577792-122602444 bp, - strand  Genetic Position: Chr6, 57.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:74021
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic fragment containing exon 6 was replaced with a neomycin selection cassette. These sequences include the majority of the coding sequences of the gene. RT-PCR analysis confirmed the absence of encoded transcript in various tissues of homozygous mice. (J:74021)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apobec1 Mutation:  8 strains or lines available
References
Original:  J:74021 Morrison JR, et al., Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7154-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory