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Apmt2FVB/NJ
QTL Variant Detail
Nomenclature
QTL variant: Apmt2FVB/NJ
Name: accelerator of polyoma-induced mammary tumors 2; FVB/NJ
MGI ID: MGI:2157318
QTL: Apmt2  Location: unknown  Genetic Position: Chr9, cM position of peak correlated region/allele: 53.48 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  FVB/NJ
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers decreased mammary tumor susceptibility.
Inheritance:    Other (see notes)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes
This allele confers decreased mammary tumor susceptibility.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:64663

A genome wide scan using 69 markers was initiated to find loci responsible for tumor acceleration in mice. A total of 126 female mice from FVB/N females X (I/LnJ females X FVB/N-TgN(MMTVPyVT)634mul males) F1 males were informative. A region of mouse Chromosome 9 including D9Mit182 was correlated with an acceleration of tumorignensis.

References
Original:  J:64663 Le Voyer T, et al., An epistatic interaction controls the latency of a transgene-induced mammary tumor. Mamm Genome. 2000 Oct;11(10):883-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory