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Apoetm2(APOE*3)Mae
Targeted Allele Detail
Nomenclature
Symbol: Apoetm2(APOE*3)Mae
Name: apolipoprotein E; targeted mutation 2, Nobuyo Maeda
MGI ID: MGI:2157240
Synonyms: 3, Apoe3, APOE3, APOE*3, apoE3-KI, apoE3 TR, Apoetm2(APOE)Mae, apoE TR, E3, TgHAPOE3N8, TgH/ApoeE3/N8, TRE3
Gene: Apoe  Location: Chr7:19696109-19699166 bp, - strand  Genetic Position: Chr7, 9.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:41705
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apoe Mutation:  59 strains or lines available
References
Original:  J:41705 Sullivan PM, et al., Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J Biol Chem. 1997 Jul 18;272(29):17972-80
All:  64 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory