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Targeted Allele Detail
Symbol: Apobec1tm1Chan
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1; targeted mutation 1, Lawrence Chan
MGI ID: MGI:2157210
Synonyms: apobec-1 -
Gene: Apobec1  Location: Chr6:122577792-122602444 bp, - strand  Genetic Position: Chr6, 57.68 cM
Germline Transmission:  Earliest citation of germline transmission: J:36051
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Part of intron 6 and exon 7 was replaced with a neomycin selection cassette. (J:36051)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apobec1 Mutation:  16 strains or lines available
Original:  J:36051 Nakamuta M, et al., Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1. J Biol Chem. 1996 Oct 18;271(42):25981-8
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory