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Targeted Allele Detail
Symbol: Amhr2tm1Bhr
Name: anti-Mullerian hormone type 2 receptor; targeted mutation 1, Richard R Behringer
MGI ID: MGI:2156555
Synonyms: Misr2-
Gene: Amhr2  Location: Chr15:102445367-102454630 bp, + strand  Genetic Position: Chr15, 57.58 cM
Germline Transmission:  Earliest citation of germline transmission: J:36027
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 4.4 kb genomic fragment containing the first six exons was deleted and replaced with a neomycin selection cassette. RT-PCR analysis demonstrated that no transcript was detectable in the urogenital ridge of homozygous E13.5 embryos. (J:36027)
View phenotypes for all genotypes (concatenated display).
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Amhr2 Mutation:  9 strains or lines available
Original:  J:36027 Mishina Y, et al., Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation. Genes Dev. 1996 Oct 15;10(20):2577-87
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory