Bglq5^LG/J
QTL Variant Detail

Summary

• QTL variant: Bglq5^LG/J
• Name: body growth late QTL 5; LG/J
• MGI ID: MGI:2156463
• QTL: Bglq5 Location: unknown Genetic Position: Chr6, cM position of peak correlated region/allele: 77.7 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: LG/J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased late growth rate compared to SM/J. (J:32208)
• Inheritance: Dominant

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:32208

Quantitative trait loci (QTLs) effecting age specific body growth rates in mice were mapped using 535 F2 intercross mice from a (LG/J x SM/J)F1 cross. LG/J mice exhibit a large size at 60 days of age whereas SM/J exhibit a Small size. QTLs on 16 of 19 autosomes effective age specific growth was detected in a genome wide scan using microsatellite markers. QTL marker Bgeq4 was associated with early growth rate and mapped to mouse Chromosome 6 near D6Nds5. A QTL marker Bglq5 was associated with late growth near D6Mit15.

J:60662

Quantitative trait loci (QTLs) effecting age specific body growth rates in mice were mapped in a previous experiment using 535 F2 intercross mice from a (LG/J x SM/J)F1 cross (See J:32208). Here an additional 510 F2 mice were analyzed. LG/J mice exhibit a large size at 60 days of age whereas SM/J exhibit a small size. QTL markers Bgeq4 and Bglq5 were reaffirmed as mapping to mouse Chromosome 6.

References

• Original: J:60662 Vaughn TT, et al., Mapping quantitative trait loci for murine growth: a closer look at genetic architecture. Genet Res. 1999 Dec;74(3):313-22
• All: 2 reference(s)