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Cdc42tm1Fwa
Targeted Allele Detail
Nomenclature
Symbol: Cdc42tm1Fwa
Name: cell division cycle 42; targeted mutation 1, Fredrick W Alt
MGI ID: MGI:2156460
Gene: Cdc42  Location: Chr4:137319696-137357720 bp, - strand  Genetic Position: Chr4, 69.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63261
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A loxP flanked neomycin selection cassette replaced the first coding exon of the gene. (J:63261)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdc42 Mutation:  40 strains or lines available
References
Original:  J:63261 Chen F, et al., Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability. Curr Biol. 2000 Jun 29;10(13):758-65
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory