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Gene trapped Allele Detail
Symbol: Gpc3Gt(Ex136)Byg
Name: glypican 3; gene trap Ex136, BayGenomics
MGI ID: MGI:2156194
Synonyms: Gpc3Gt(pGT1.8TM)136Wcs, Gpc3TgN(betageo)ex136Ska
Gene: Gpc3  Location: ChrX:52272426-52613950 bp, - strand  Genetic Position: ChrX, 28.74 cM, cytoband A3.3
Mutant Cell Line:  Ex136 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:64330
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT1tfr
Mutation detailsThe gene trap vector pGT1tfr was inserted into intron 2. Western blot analysis on purified proteoglycan extracts derived from E16.5 liver of male hemizygous mice confirmed that no detectable protein is produced from this allele. (J:64330)
Inheritance:    Recessive
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpc3 Mutation:  16 strains or lines available
Original:  J:70273 Mitchell KJ, et al., Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet. 2001 Jul;28(3):241-9
All:  3 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory