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Acvrl1tm1Dyl
Targeted Allele Detail
Nomenclature
Symbol: Acvrl1tm1Dyl
Name: activin A receptor, type II-like 1; targeted mutation 1, Dean Y Li
MGI ID: MGI:2155981
Synonyms: Alk1-
Gene: Acvrl1  Location: Chr15:101128522-101145336 bp, + strand  Genetic Position: Chr15, 56.41 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65521
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation detailsThe mutation disrupted trancriptional and translational initiation. No specific molecular details were described. In situ hybridization experiments confirmed that expression of the transcript is undetectable in homozygous mice. (J:65521, J:85366)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acvrl1 Mutation:  8 strains or lines available
References
Original:  J:65521 Urness LD, et al., Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000 Nov;26(3):328-31
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory