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Hsf1tm1Ijb
Targeted Allele Detail
Nomenclature
Symbol: Hsf1tm1Ijb
Name: heat shock factor 1; targeted mutation 1, Ivor J Benjamin
MGI ID: MGI:2155444
Synonyms: Hsf1-
Gene: Hsf1  Location: Chr15:76477445-76500972 bp, + strand  Genetic Position: Chr15, 35.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73593
Parent Cell Line:  KG-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 78 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hsf1 Mutation:  7 strains or lines available
References
Original:  J:73593 McMillan DR, et al., Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis. J Biol Chem. 1998 Mar 27;273(13):7523-8
All:  39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory