About   Help   FAQ
Snrpntm2Cbr
Targeted Allele Detail
Nomenclature
Symbol: Snrpntm2Cbr
Name: small nuclear ribonucleoprotein N; targeted mutation 2, Camilynn I Brannan
MGI ID: MGI:2155245
Synonyms: deltaPWS-IC, IC deletion, PWS-ICdel, PWS-ICdel35kb, PWS-IC deletion
Gene: Snrpn  Location: Chr7:59982495-60005111 bp, - strand  Genetic Position: Chr7, 34.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:47318
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snrpn Mutation:  7 strains or lines available
Notes
ES cell line = CJ7 or J4. In J:47318 CJ7 male ES cells were used. All offspring generated from crosses of these chimeras to C57BL/6 females died by postnatal day 7. In J:61887 the same targeting vector was used in CJ7 (male) and J4 (female, XO) ES cells. It is unclear which of these targeting events was used to generate the line of mice used in subsequent papers as both parental inheritence of the allele and strain background influence the survival of offspring.

References
Original:  J:47318 Yang T, et al., A mouse model for Prader-Willi syndrome imprinting-centre mutations. Nat Genet. 1998 May;19(1):25-31
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory