About   Help   FAQ
QTL Variant Detail
QTL variant: EtohrC57BL/6J
Name: ethanol response acute; C57BL/6J
MGI ID: MGI:2155093
QTL: Etohr  Location: Chr2:80175610-80175769 bp  Genetic Position: Chr2, cM position of peak correlated region/allele: 47.93 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Strain of Specimen:  C57BL/6J
Allele Type:    QTL
Mutation:    Undefined
Mutation detailsThis allele confers decreased locomotor activity in response to alcohol challenge compared to DBA/2J. (J:52042)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).

Mapping and Phenotype information for this QTL, its variants and associated markers


Changes in locomotor activity due to ethanol was analysed in BXD RI stains and in 900 F2 (C57BL/6J x DBA/2J) intercross mice. The RI data provided a suggestive association of the locomotor response with markers on various chromosomes including mouse Chromosome 2. The mouse Chromosome 2 location was verified in the F2 cross and reached a level of significance when combined with the RI data. The activity QTL (Etohr) on mouse chromosome 2 had a peak LOD of 5.3 with an approximate cM position of 48 and was associated with markers D2Mit94 and D2Mit420.

Original:  J:52042 Demarest K, et al., Identification of an acute ethanol response quantitative trait locus on mouse chromosome 2. J Neurosci. 1999 Jan 15;19(2):549-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.16
The Jackson Laboratory