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Cyp19a1tm1Esi
Targeted Allele Detail
Nomenclature
Symbol: Cyp19a1tm1Esi
Name: cytochrome P450, family 19, subfamily a, polypeptide 1; targeted mutation 1, Evan R Simpson
MGI ID: MGI:2154536
Synonyms: ArKO
Gene: Cyp19a1  Location: Chr9:54165937-54193442 bp, - strand  Genetic Position: Chr9, 29.49 cM
Increased adipocyte size in Cyp19a1tm1Esi/Cyp19a1tm1Esi mice

Show the 3 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48086
Parent Cell Line:  KG-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cyp19a1 Mutation:  12 strains or lines available
References
Original:  J:48086 Fisher CR, et al., Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6965-70
All:  49 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory