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Fgfr2tm2.1Dsn
Targeted Allele Detail
Nomenclature
Symbol: Fgfr2tm2.1Dsn
Name: fibroblast growth factor receptor 2; targeted mutation 2.1, Clive Dickson
MGI ID: MGI:2153814
Synonyms: FgfR2-IIIcneo-deltaflox
Gene: Fgfr2  Location: Chr7:130162451-133123350 bp, - strand  Genetic Position: Chr7, 73.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72517
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is a derivative of Fgfr2tm2Dsn in which the exon 9 sequences were deleted by crossing mice carrying the Fgfr2tm2Dsn allele to mice which expresss Cre recombinase in the germ line. (J:72517)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr2 Mutation:  41 strains or lines available
References
Original:  J:72517 Hajihosseini MK, et al., A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3855-60
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory