Tyr^c-2MLPm
Chemically induced Allele Detail

Summary

• Symbol: Tyr^c-2MLPm
• Name: tyrosinase; albino deletion 2MLPm, Oak Ridge
• MGI ID: MGI:2153745
• Synonyms: c^2MLPm, c^OR-2Mm
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^c-2MLPm page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intergenic deletion
• Large intergenic deletion.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 375 strains or lines available

Notes

The chemical mutagen used was melphalan.

References

• Original: J:24557 Russell LB, et al., Genetic, cytogenetic, and molecular analyses of mutations induced by melphalan demonstrate high frequencies of heritable deletions and other rearrangements from exposure of postspermatogonial stages of the mouse. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6182-6
• All: 2 reference(s)