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Fgfr1tm5Jrt
Targeted Allele Detail
Nomenclature
Symbol: Fgfr1tm5Jrt
Name: fibroblast growth factor receptor 1; targeted mutation 5, Janet Rossant
MGI ID: MGI:2153349
Synonyms: n15
Gene: Fgfr1  Location: Chr8:25513654-25575714 bp, + strand  Genetic Position: Chr8, 14.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49154
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Hypomorph)
Mutation:    Insertion
    A loxP flanked neomycin cassette was inserted into intron 15. This is a hypomorphic allele. (J:49154)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  172 strains or lines available
References
Original:  J:49154 Partanen J, et al., Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev. 1998 Aug 1;12(15):2332-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory