About   Help   FAQ
Cspg4tm1Wbst
Targeted Allele Detail
Nomenclature
Symbol: Cspg4tm1Wbst
Name: chondroitin sulfate proteoglycan 4; targeted mutation 1, William B Stallcup
MGI ID: MGI:2153094
Synonyms: NG2-
Gene: Cspg4  Location: Chr9:56865104-56899870 bp, + strand  Genetic Position: Chr9, 30.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:54319
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin resistance cassette was inserted into exon 3. Western blot analysis of P4 brain extracts using a rabbit antibody did not detect protein in homozygous mutant mice. Immunohistochemical studies of aortic smooth muscle cells did not detect protein in P1 homozygous mutant mice. (J:54319)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cspg4 Mutation:  47 strains or lines available
References
Original:  J:54319 Grako KA, et al., PDGF (alpha)-receptor is unresponsive to PDGF-AA in aortic smooth muscle cells from the NG2 knockout mouse. J Cell Sci. 1999 Mar;112(Pt 6):905-15
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/14/2017
MGI 6.08
The Jackson Laboratory