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Vwftm1Wgr
Targeted Allele Detail
Nomenclature
Symbol: Vwftm1Wgr
Name: Von Willebrand factor homolog; targeted mutation 1, Denisa D Wagner
MGI ID: MGI:2153009
Synonyms: vWf-, VWF KO
Gene: Vwf  Location: Chr6:125546774-125686679 bp, + strand  Genetic Position: Chr6, 59.32 cM
Spontaneous bleeding events in Vwftm1Wgr/Vwftm1Wgr mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49083
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vwf Mutation:  23 strains or lines available
References
Original:  J:49083 Denis C, et al., A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9524-9
All:  54 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory