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Lhx5tm1Lmgd
Targeted Allele Detail
Nomenclature
Symbol: Lhx5tm1Lmgd
Name: LIM homeobox protein 5; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID: MGI:2152620
Synonyms: Lhx5-, Lhx5 KO
Gene: Lhx5  Location: Chr5:120431699-120441223 bp, + strand  Genetic Position: Chr5, 60.62 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:55103
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 2, 3, and 4 of the gene, which encode the second LIM domain and the homeodomain of the protein. (J:55103)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx5 Mutation:  9 strains or lines available
References
Original:  J:55103 Zhao Y, et al., Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Science. 1999 May 14;284(5417):1155-8
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory