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Hoxd8tm1Jdes
Targeted Allele Detail
Nomenclature
Symbol: Hoxd8tm1Jdes
Name: homeobox D8; targeted mutation 1, Jacqueline Deschamps
MGI ID: MGI:2151815
Gene: Hoxd8  Location: Chr2:74704615-74707933 bp, + strand  Genetic Position: Chr2, 44.13 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:68720
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin cassette was inserted into the sequences in exon 2 which encode the homeodomain. (J:68720)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxd8 Mutation:  0 strains or lines available
References
Original:  J:68720 van den Akker E, et al., Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes. Development. 2001 May;128(10):1911-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory