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Msh6tm1Htr
Targeted Allele Detail
Nomenclature
Symbol: Msh6tm1Htr
Name: mutS homolog 6 (E. coli); targeted mutation 1, Hein te Riele
MGI ID: MGI:2151803
Gene: Msh6  Location: Chr17:87975050-87990883 bp, + strand  Genetic Position: Chr17, 57.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59561
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Part of exon 4 was replaced with a vector containing the puromycin resistance gene. (J:59561)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msh6 Mutation:  10 strains or lines available
References
Original:  J:59561 de Wind N, et al., HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet. 1999 Nov;23(3):359-62
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory