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Gna13tm1Soff
Targeted Allele Detail
Nomenclature
Symbol: Gna13tm1Soff
Name: guanine nucleotide binding protein, alpha 13; targeted mutation 1, Stefan Offermanns
MGI ID: MGI:2151775
Synonyms: Galpha13-
Gene: Gna13  Location: Chr11:109362831-109401369 bp, + strand  Genetic Position: Chr11, 71.88 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50566
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic fragment containing the first exon was replaced with a neomycin cassette. RT-PCR analysis did not detect a transcript produced from this allele in homozygous mice. (J:50566)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gna13 Mutation:  6 strains or lines available
References
Original:  J:50566 Offermanns S, et al., Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science. 1997 Jan 24;275(5299):533-6
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory