About   Help   FAQ
Hoxb2tm1Fmr
Targeted Allele Detail
Nomenclature
Symbol: Hoxb2tm1Fmr
Name: homeobox B2; targeted mutation 1, Filippo M Rijli
MGI ID: MGI:2151774
Synonyms: Hoxb2-
Gene: Hoxb2  Location: Chr11:96351632-96354020 bp, + strand  Genetic Position: Chr11, 59.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:54652
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ gene was inserted in frame into exon 1, replacing 300 bp of exonic/intronic sequence. A neomycin cassette was inserted following the lacZ gene. (J:54652)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 57 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb2 Mutation:  1 strain or line available
References
Original:  J:54652 Davenne M, et al., Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron. 1999 Apr;22(4):677-91
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/26/2020
MGI 6.15
The Jackson Laboratory