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Hcrttm1Ywa
Targeted Allele Detail
Nomenclature
Symbol: Hcrttm1Ywa
Name: hypocretin; targeted mutation 1, Masashi Yanagisawa
MGI ID: MGI:2151182
Synonyms: OKO, orexin knockout, orexin KO, orexin-tau-LacZ, ORX-KO, Ox-
Gene: Hcrt  Location: Chr11:100761069-100762931 bp, - strand  Genetic Position: Chr11, 63.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57124
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hcrt Mutation:  30 strains or lines available
References
Original:  J:57124 Chemelli RM, et al., Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation [see comments]. Cell. 1999 Aug 20;98(4):437-51
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory