Dnajb6^{Gt(ROSABetageo)6AD1Jcc}
Gene trapped Allele Detail

Summary

• Symbol: Dnajb6^{Gt(ROSABetageo)6AD1Jcc}
• Name: DnaJ heat shock protein family (Hsp40) member B6; gene trap 6AD1, James C Cross
• MGI ID: MGI:2151092
• Synonyms: 6AD1betageo, Mrj, Mrj^-
• Gene: Dnajb6 Location: Chr5:29940896-29991476 bp, + strand Genetic Position: Chr5, 15.27 cM, cytoband B1
• Alliance: Dnajb6^{Gt(ROSABetageo)6AD1Jcc} page

Mutation origin

• Mutant Cell Line: 6AD1
• Germline Transmission: Earliest citation of germline transmission: J:52602
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSABetageo Vector Type: gene trap
• Mutation details: Insertion of a complete copy of gene trap vector ROSA Beta-geo cassette into intron 1. Northern blots of E10.5 placental RNA and in situ hybridization analyses on E8.5 embryos failed to detect any transcript in homozygotes. (J:40477, J:52602)

Expression

In Mice Carrying this Mutation:	90 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnajb6 Mutation: 72 strains or lines available

References

• Original: J:52602 Hunter PJ, et al., Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development. Development. 1999 Mar;126(6):1247-58
• All: 6 reference(s)