Hoxb7^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxb7^tm1Mrc
• Name: homeobox B7; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:2150401
• Synonyms: Hoxb7 -
• Gene: Hoxb7 Location: Chr11:96177449-96180988 bp, + strand Genetic Position: Chr11, 59.82 cM
• Alliance: Hoxb7^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:50942
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into the sequences encoding the homeobox domain. (J:50942)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb7 Mutation: 14 strains or lines available

References

• Original: J:50942 Chen F, et al., Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae. Mech Dev. 1998 Sep;77(1):49-57
• All: 1 reference(s)