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Giprtm1Yse
Targeted Allele Detail
Nomenclature
Symbol: Giprtm1Yse
Name: gastric inhibitory polypeptide receptor; targeted mutation 1, Yutaka Seino
MGI ID: MGI:2149964
Synonyms: GIPR-
Gene: Gipr  Location: Chr7:18889986-18900052 bp, - strand  Genetic Position: Chr7, 9.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59087
Parent Cell Line:  CGR8 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin cassette replaced exons 4 and 5 of the gene, which encode the N-terminal extracellular region of the protein. No functional protein product is expressed from this allele. (J:59087)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gipr Mutation:  22 strains or lines available
References
Original:  J:59087 Miyawaki K, et al., Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14843-7
All:  44 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory