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Hes1tm1Fgu
Targeted Allele Detail
Nomenclature
Symbol: Hes1tm1Fgu
Name: hairy and enhancer of split 1 (Drosophila); targeted mutation 1, Francois Guillemot
MGI ID: MGI:2149672
Synonyms: Hes1-
Gene: Hes1  Location: Chr16:30064384-30067796 bp, + strand  Genetic Position: Chr16, 21.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30431
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 41 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hes1 Mutation:  10 strains or lines available
References
Original:  J:30431 Ishibashi M, et al., Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 1995 Dec 15;9(24):3136-48
All:  57 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory