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Add2tm1Llp
Targeted Allele Detail
Nomenclature
Symbol: Add2tm1Llp
Name: adducin 2 (beta); targeted mutation 1, Luanne L Peters
MGI ID: MGI:2149065
Synonyms: band 3-, beta-adducin-
Gene: Add2  Location: Chr6:86078084-86119555 bp, + strand  Genetic Position: Chr6, 37.55 cM
Red blood cell and histological spleen comparison of Add2tm1Llp/Add2tm1Llp and +/+ wildtype mouse.

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71029
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Add2 Mutation:  3 strains or lines available
References
Original:  J:71029 Gilligan DM, et al., Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice. Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10717-22
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory