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Maftm1Gsb
Targeted Allele Detail
Summary
Symbol: Maftm1Gsb
Name: MAF bZIP transcription factor; targeted mutation 1, Gregory S Barsh
MGI ID: MGI:2148635
Synonyms: MaflacZ
Gene: Maf  Location: Chr8:116429992-116433633 bp, - strand  Genetic Position: Chr8, 62.61 cM
Alliance: Maftm1Gsb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56583
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of sequences encoding the C-terminal 351 amino acids with a lacZ gene. This allele expresses a fusion protein of the first 19 amino acids of MAF fused to beta-galactosidase. (J:56583)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 137 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Maf Mutation:  26 strains or lines available
References
Original:  J:56583 Ring BZ, et al., Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development. 2000 Jan;127(2):307-17
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory